Table 3 Significant genetic loci for competition of E. coli with P. aeruginosa in the presence of 4% glucose

tolC

Transport channel

-2.612

1.90E-268

aspA

Aspartate ammonia-lyase

1.669

3.45E-88

gltA

Citrate synthase

1.431

3.12E-76

cyaA

Adenylate cyclase

1.105

2.78E-71

sucA

2-oxoglutarate decarboxylase; thiamine triphosphate-binding

2.235

7.40E-54

sdhA

Succinate dehydrogenase; flavoprotein subunit

1.758

5.98E-51

atpA

F1 sector of membrane-bound ATP synthase alpha subunit

1.615

9.95E-49

treC

Trehalose-6-P hydrolase

1.051

8.17E-47

sucC

Succinyl-CoA synthetase beta subunit

1.318

1.29E-41

mdh

Malate dehydrogenase; NAD(P)-binding

1.601

1.33E-37

sucD

Succinyl-CoA synthetase; NAD(P)-binding; alpha subunit

1.399

9.95E-33

aspC

Aspartate aminotransferase; PLP-dependent

1.147

3.08E-31

rpoS

RNA polymerase sigma S (sigma 38) factor

-1.376

7.68E-31

nuoG

NADH:ubiquinone oxidoreductase chain G

1.479

3.69E-29

atpD

F1 sector of membrane-bound ATP synthase beta subunit

1.724

7.65E-29

nuoL

NADH:ubiquinone oxidoreductase membrane subunit L

1.461

1.09E-28

trkA

NAD-binding component of TrK potassium transporter

1.086

1.10E-28

acnB

Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase

1.426

2.37E-26

nuoF

NADH:ubiquinone oxidoreductase chain F

1.887

4.37E-23

nuoC

NADH:ubiquinone oxidoreductase; fused CD subunit

1.629

2.42E-22

sdhB

Succinate dehydrogenase FeS subunit

1.439

3.13E-21

nuoJ

NADH:ubiquinone oxidoreductase; membrane subunit J

1.836

3.15E-21

lon

DNA-binding ATP-dependent protease La

1.061

5.30E-20

nuoN

NADH:ubiquinone oxidoreductase; membrane subunit N

1.652

1.38E-18

nuoB

NADH:ubiquinone oxidoreductase; chain B

1.847

1.38E-18

nuoM

NADH:ubiquinone oxidoreductase; membrane subunit M

1.685

1.00E-15

atpB

F0 sector of membrane-bound ATP synthase subunit a

1.812

5.82E-12

waaC

ADP-heptose:LPS heptosyl transferase I

-1.099

1.49E-09

nuoH

NADH:ubiquinone oxidoreductase; membrane subunit H

1.749

7.08E-09

sdhC

Succinate dehydrogenase; membrane subunit; binds cytochrome b556

1.566

1.57E-08

atpG

F1 sector of membrane-bound ATP synthase; gamma subunit

1.611

2.13E-08

atpC

F1 sector of membrane-bound ATP synthase; epsilon subunit

1.434

2.28E-08

sdhD

Succinate dehydrogenase; membrane subunit; binds cytochrome b556

1.525

9.15E-08

rseA

Anti-sigma factor

-1.021

5.24E-07

atpF

F0 component of proton translocating ATPase subunit b

1.416

8.52E-07

nusA

Transcription termination/antitermination L factor

1.279

2.19E-06

sdhE

Flavinator of succinate dehydrogenase; antitoxin of CptAB toxin-antitoxin pair

1.333

7.82E-06

ihfB

Integration host factor (IHF); DNA-binding protein; beta subunit

-1.117

9.13E-06

fis

Global DNA-binding transcriptional dual regulator

-1.099

2.03E-05

ruvB

ATP-dependent DNA helicase; component of RuvABC resolvasome

-1.132

8.19E-05

hscA

DnaK-like molecular chaperone specific for IscU

1.205

0.0001

atpE

F0 sector of membrane-bound ATP synthase; subunit c

1.110

0.0003

ddlB

D-alanine:D-alanine ligase

-1.071

0.0003

sucB

Dihydrolipoyltranssuccinase

1.089

0.0004

atpH

F1 sector of membrane-bound ATP synthase; delta subunit

1.351

0.0008

yzgL

Putative uncharacterised protein

1.025

0.0060