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Table 4 Inhibition of AFB1 production in A. parasiticus NRRL 2999 by the ethyl acetate (EtOAc) extract of Platycladus orientalis leaves. Fungal growth was stimulated by the plant extract to a significant degree at the highest concentration of 2,000 μg/ml

From: Search for novel antifungals from 49 indigenous medicinal plants: Foeniculum vulgare and Platycladus orientalis as strong inhibitors of aflatoxin production by Aspergillus parasiticus

Plant EtOAc extract concentration (μg/ml)

Fungal dry weight (DW; mg)

AFB1 (μg/mg fungal DW)

Mean ± SD

Mean ± SD

Inhibition (%)

0.0

11.03 ± 1.25

1.88 ± 0.44

0.00

15.62

9.23 ± 0.31

1.39 ± 0.27

26.06

31.25

9.20 ± 0.90

1.29 ± 0.12*

31.38

62.50

9.57 ± 0.81

0.85 ± 0.03*

54.79

125

10.15 ± 1.09

0.76 ± 0.08*

59.57

250

13.06 ± 1.40

0.67 ± 0.10*

64.36

500

13.10 ± 0.85

0.67 ± 0.09*

64.36

1,000

13.20 ± 0.87

0.30 ± 0.04*

84.04

2,000

18.00 ± 1.87*

0.19 ± 0.02*

89.89

  1. *Statistically significant difference with a control (ANOVA; P < 0.05); there was no further significant inhibition of AFB1 production at plant extract concentrations > 2,000 μg/ml