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Table 2 Alpha-glucosidase inhibition of ethyl acetate partition extract from fermentation broth (BE) obtained from N. sphaerica

From: Evaluation of in vitro alpha-glucosidase inhibitory, antimicrobial, and cytotoxic activities of secondary metabolites from the endophytic fungus, Nigrospora sphaerica, isolated from Helianthus annuus

Sample

% inhibitory concentration (μg/mL)

IC50 (μg/mL)

250

125

62.50

31.25

15.63

7.81

3.90

1.95

Extract

91.70 ± 2.40

82.75 ± 1.50

75.67 ± 1.50

69.71 ± 1.16

65.23 ± 0.52

45.56 ± 0.14

40.22 ± 0.11

38.10 ± 0.04

17.25

Acarbose

98.92 ± 3.55

97.25 ± 2.81

96.20 ± 2.11

85.35 ± 1.95

67.50 ± 1.11

65.20 ± 0.52

55.75 ± 0.12

49.20 ± 0.05

4.20