Safety assessment of Lactobacillus reuteri IDCC 3701 based on phenotypic and genomic analysis

Annals of Microbiology

Table 2 Minimal inhibitory concentrations and antibiotic resistance gene of L. reuteri IDCC 3701

Antibiotic^a	AMP	VAN	GEN	KAN	STR	ERY	CLI	TET	CHL
Cut-off value^b (μg/mL)	2	n.r^c	8	64	64	1	4	32	4
Observed MIC	0.5	512	16	256	32-64	0.125-0.5	0.125-0.5	4	4
Assessment	S^d	n.r	R^e	R	S	S	S	S	S
Antibiotic resistance gene	n.d^f	n.d	n.d	n.d	n.d	n.d	n.d	n.d	n.d

^aAMP ampicillin, VAN vancomycin, GEN gentamicin, KAN kanamycin, STR streptomycin, ERY erythromycin, CLI clindamycin, TET tetracycline, CHL chloramphenicol
^b EFSA (European Food Safety Authority) Guidelines, 2018. EFSA Journal, 16(3), 5206
^cn.r not required
^dS susceptible
^eR resistant
^fn.d not detected

ISSN: 1869-2044