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Table 3 FPKM values of CoQ10 synthesis-related genes based on RNA-seq analysis

From: Co-production of polyhydroxybutyrate (PHB) and coenzyme Q10 (CoQ10) via no-sugar fermentation—a case by Methylobacterium sp. XJLW

Locus

Genes

Enzymes

FPKM in glucose

FPKM in methanol

Log2 FPKM (M/G)

Up or down

A3862_RS14500

dxr

1-Deoxy-D-xylulose-5-phosphate reductoisomerase

99.9563

148.212

0.568293

Up

A3862_RS20315

ispDF

Bifunctional 2-C-methyl-D-erythritol 4-phosphate Cytidylyltransferase/2-C-methyl-D-erythritol 2,4-Cyclodiphosphate synthase

92.8581

149.282

0.684941

Up

A3862_RS03995

ispE

4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase

64.3157

141.036

1.132821

Up

A3862_RS12025

ispG

Flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase

425.885

296.847

− 0.52074

Down

A3862_RS10000

ispH

4-Hydroxy-3-methylbut-2-enyl diphosphate reductase

1071.31

683.363

− 0.64865

Down

A3862_RS18005

ggps

Geranylgeranyl diphosphate synthase, type II

30.1079

127.672

2.084228

Up

A3862_RS28415

ispA

Polyprenyl synthetase family protein

200.033

143.273

− 0.48147

Down

A3862_RS04015

ispB

Polyprenyl synthetase family protein

95.6316

164.97

0.786644

Up

A3862_RS03825

ubiA

4-Hydroxybenzoate octaprenyltransferase

73.9099

148.495

1.006575

Up

A3862_RS05140

ubiX

UbiX family flavin prenyltransferase

43.2101

92.1585

1.092749

Up

A3862_RS05150

ubiD

UbiD family decarboxylase

30.4548

120.907

1.989156

Up

A3862_RS18730

ubiI

2-Polyprenylphenol 6-hydroxylase

54.8386

146.31

1.415765

Up

A3862_RS01610

ubiG

Bifunctional 2-Polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG

68.382

118.171

0.789188

Up

A3862_RS13590

ubiH

FAD-dependent monooxygenase

65.993

170.113

1.366108

Up

A3862_RS18735

ubiE

Bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE

99.1489

146.834

0.566517

Up

A3862_RS22985

ubiF

UbiH/UbiF family hydroxylase

84.6668

194.111

1.197014

Up