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Table 2 Bioactive compounds produced by the Bacillus species and its health benefits

From: Impact of Bacillus in fermented soybean foods on human health

Microorganisms

Bioactive compounds

Health benefits

References

Bacillus species

Poly-γ-glutamic acid

Suppression in the elevation of post prandial blood glucose level

Chettri et al. (2016)

Bacillus species

Isoflavone aglycone

Flavonoid bioconversion

Kim et al. (2018)

Bacillus species LM7

Bacillomycin D and surfactin

Antimicrobial activity

Lee et al. (2016a, 2016b)

Bacillus subtilis var. natto

Nattokinase and serine protease subtilisin

Fibrinolytic activity and tissue plasminogen activator can be increased

Mohanasrinivasan et al. (2017)

Bacillus subtilis 1423

Protease

Breaks down the complex protein to simpler molecules

Nguyen and Nguyen (2020)

Bacillus subtilis DC27

Serine protease

Fibrinolytic activity

Hu et al. (2019)

Bacillus subtilis natto O9516

ACE inhibitory peptides

Anti-hypertensive activity

Ibe et al. (2009)

Bacillus subtilis

Nattokinase

Anti-hyperlipidemic activity

Chen et al. (2018)

Bacillus natto TK-1

Lipopeptide

Biosurfactant activity

Cao et al. (2009)

Bacillus subtilis

Protease and esterase

Degradation of proteins and fats

Sanjukta and Rai (2016)

Bacillus subtilis

Proteolytic enzymes

Glycinin and β -conglycinin hydrolyzed for the production of bioactive peptides

Sanjukta and Rai (2016)

Bacillus subtilis var. natto

PGA and fructan (mucilage)

Antioxidant properties

Chettri and Tamang (2014)

Bacillus subtilis SN7

Bacteriocin

Biocontrol agent

Lee and Chang (2017)

Bacillus subtilis CSY 191

Surfactin

Inhibits growth of human breast cancer cells (MCF-7)

Lee et al. (2012)

Bacillus subtilis (natto)

Lipoproteins

Anti-inflammatory response

Rhayat et al. (2019)

Bacillus subtilis SHZ

Bioactive peptide and polyphenols

Antioxidant activity

Sanjukta and Rai (2016)

Bacillus subtilis N205 (BS205)

Isoflavone aglycones

Antioxidant properties

Ping et al. (2012)

Bacillus subtilis-SKm (BS-c)

α-amylase, and γ-GTP

Antioxidant property

Zheng et al. (2011)

Bacillus subtilis SC-8

Surfactin, fengycin and iturin.

Antifungal and antibiotic properties

Yeo et al. (2011a, 2011b)

Bacillus subtilis NT-6

Amphipathic peptide AMPNT-6

Antimicrobial effect

Xu et al. (2013)

Bacillus subtilis SCK-2

Peptide AMPC IC-1

Antimicrobial properties

Yeo et al. (2011a, 2011b)

Bacillus amyloliquefaciens FZB42

Fibrinolytic enzymes

Fibrinolytic activity

Huy et al. (2016)

Bacillus amyloliquefacians EMD 17

Surfactin

Antimicrobial activity

Lee et al. (2016a, 2016b)

Bacillus amyloliquefacians

Daidzein

Anti-diabetic property

Jeong et al. (2020)

Bacillus amyloliquefacians

1-Deoxynojirimycin

Alpha-glucosidase inhibitor

Cai et al. (2017)

Bacillus amyloliquefaciens SWJS22

β-glucosidase and protease

Antioxidant activity

Yang et al. (2019a, 2019b)

Bacillus amyloliquefaciens RWL-1

Isoflavones and phenolic contents

Antioxidant properties

Shahzad et al. (2020)

Bacillus amyloliquefaciens

Genistein

Neuroprotective effect

Khosravi and Razavi (2021)

Bacillus licheniformis B65-1

Phenylacetic acid

Inhibition of enteric pathogens

Kim et al. (2004)

Bacillus licheniformis 67

Poly-γ-glutamic acid

Anti-obesity effect

Choi et al. (2016)

Bacillus licheniformis (SFC)

Isoflavones aglycones

Anti-diabetic effect

Yang et al. (2014)