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Table 1 Conditions for UV mutationa

From: Production of lovastatin by a self-resistant mutant of Aspergillus terreus

Run of mutagenesisb

UV mutation (min)

Dark reparation

Lov-resistant level (g l−1)

1

3

28°C, 150g, 24 h, dark

0.25

2

1

28°C, 150g, 24 h, dark

0.5

3

1

28°C, 150g, 24 h, dark

1.0

4

1.5

28°C, 150g, 8 h, dark

4.0

  1. aEach run of mutagenesis were all started from 45 s of UV irradiation, followed by 30 min of light reparation before UV mutation
  2. bEach cycle of mutation was originated from the former strain