Skip to main content

Table 3 Optimization of carbon sources for cell growth and lovastatin production by submerged cultivation of the parent strain and the mutant of A. terreus a

From: Production of lovastatin by a self-resistant mutant of Aspergillus terreus

Carbon source b

ATCC 20542

LA4414

Biomass (g DCW l−1)

Lovastatin production (mg l−1)

Biomass (g DCW l−1)

Lovastatin production (mg l−1)

Glycerol

12.68 ± 0.18

448.3 ± 9.7

11.52 ± 0.45

935.3 ± 21.4

Glucose

14.15 ± 0.09

177.5 ± 12.4

5.65 ± 0.10

112.3 ± 11.8

Sucrose

13.48 ± 0.22

243.2 ± 15.3

7.10 ± 0.20

218.8 ± 6.3

Lactose

4.29 ± 0.13

305.0 ± 6.4

2.10 ± 0.25

212.4 ± 11.6

Soluble starch

17.48 ± 0.32

165.2 ± 14.3

10.70 ± 0.10

502.5 ± 22.4

  1. a10 g l-1 of yeast extract powder was regarded as the sole complex nitrogen source in all experiments
  2. bThe 20 g l-1 of carbon content for each carbon source was used. The actual concentrations were 51.2, 55, 47.5, 50, and 45 g l-1, respectively
  3. cThe maximum errors were calculated from 3 independent samples
Back to article page

Annals of Microbiology

ISSN: 1869-2044

Contact us