Fermentation characteristics and hypoglycemic activity of an exopolysaccharide produced by submerged culture of Stropharia rugosoannulata #2

Table 1 Experimental groups for testing the dose-dependent hypoglycemic activity of Stropharia rugosoannulata extracellular polysaccharides

Group	Oral administration
Normal^a	None
Control^b	0.9 % NaCl
Low-treated (L)^b	50 mg/kg day S. rugosoannulata EPS
Medium-treated (M)^b	100 mg/kg day S. rugosoannulata EPS
Hight-treated (H)^b	200 mg/kg day S. rugosoannulata EPS

EPS, Extracellular polysaccharide
^aGroup of 8 normal rats
^bRats in which diabetics had been induced by streptozotocin injections (50 mg/kg body weight). Each group consisted of 8 rats. The rats were administered daily doses of either saline (control) or EPS produced from the submerged mycelial culture of S. rugosoannulata at 50–200 mg/kg body weight daily for 3 weeks

ISSN: 1869-2044