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Table 3 Biotransformation of halogen derivatives of acetophenone (1) by selected strains of Y. lipolytica

From: Biotransformation of acetophenone and its halogen derivatives by Yarrowia lipolytica strains

Strain

Substratea

Day

Conversion by GC (%)b

ee (%)

Configuration

B56-5

3

1

100

63

S

A18

1

99

68

S

ATCC 32-338A

1

20 ± 3

65

R

9

27 ± 4

67

R

A50

1

58 ± 2

31

S

A-101

1

100

86

S

B56-5

4

1

89 ± 1

39

R

 

3

100

42

R

A18

1

58 ± 2

31

R

 

9

88 ± 1

47

R

ATCC 32-338A

1

24 ± 4

2

S

 

3

62 ± 1

10

S

A50

1

57 ± 2

46

R

 

9

100

48

R

A-101

1

100

69

R

B56-5

5

1

98 ± 1

68

S

A18

1

59 ± 3

54

S

 

9

71 ± 3

53

S

ATCC 32-338A

1

11 ± 1

37

R

 

9

12 ± 1

48

R

A50

1

39 ± 2

48

S

 

9

55 ± 1

47

S

A-101

1

92 ± 1

80

S

B56-5

6

1

100

12

S

A18

1

100

2

R

ATCC 32-338A

1

100

74

S

A50

1

100

60

R

A-101

1

100

16

S

 

9

100

55

S

B56-5

7

1

100

14

R

A18

1

100

9

R

ATCC 32-338A

1

64 ± 3

100

R

 

3

100

100

R

A50

3

100

22

R

A-101

1

100

3

S

  1. a(3), 2,4′-dichloroacetophenone; (4), 2,2′,4′-trichloroacetophenone; (5), 2-chloro-4′-fluoroacetophenone; (6), 2-bromo-4′-chloroacetophenone; (7), 2,4′-dibromoacetophenone
  2. bValues reported as the mean ± SD