Fig. 2

a Cytotoxic effect of activated proteins from B.t.LDC 501, reference strain B. thuringiensis israelensis (BGSC-4Q2) and a mock (Mock inoculated; solubilization buffer + proteinase K)-inoculated sample against human cancer cell lines (SiHa, HCT 116), normal murine fibroblasts (NIH/3T3) and human peripheral blood leukocytes. b Cytopathic effect of activated proteins from B.t.LDC 501, BGSC-4Q2 and mock-inoculated sample against human colon cancer cell lines (SW480, SW620), normal human embryonic kidney (HEK293) and human corneal epithelial (HCEC) cell lines. c Dose–response curves of cytotoxic effect induced by B.t.LDC 501-activated proteins against HCT 116, SW480, SW620, SiHa, NIH/3T3, human peripheral blood leukocytes, HEK293 and HCEC. The level of cytotoxicity was assessed with the MTT assay at 16 h post inoculation. Each point represents mean ± standard error (SE) (n = 3). Different lowercase letters above symbols indicate statistical significance at p ≤ 0.05 between the respective groups by the Tukey test