Comparative transcriptomic analysis of Listeria monocytogenes reveals upregulation of stress genes and downregulation of virulence genes in response to essential oil extracted from Baccharis psiadioides

Table 4 Number of down and upregulated genes related to processes belonging to the functional categories studied [Biological Process (BP); Cellular Component (CC); Molecular Function MF)] in Listeria monocytogenes 55 grown in the presence of EOBp

	Down	Up
BP
Biological regulation	4	12
Biopolymer metabolic process	41	18
Biosynthetic process	82	74
Carbohydrate metabolic process	41	56
Catabolic process	15	25
Cell adhesion	2	2
Cell communication	1	1
Cell cycle	0	4
Cell division	45	35
Cell motility	2	3
Cellular amino acid and derivative metabolic process	19	33
Cellular developmental process	1	1
Cellular metabolic process	101	90
Cellular process	110	104
Chromosome organization	2	0
Chromosome segregation	1	0
Cofactor metabolic process	12	18
Gene expression	34	4
Generation of precursor metabolites and energy	9	10
Homeostatic process	4	11
Lipid metabolic process	2	10
Localization	16	14
Macromolecule metabolic process	41	18
Metabolic process	122	122
Nitrogen compound metabolic process	67	78
Nucleobase, nucleoside, nucleotide and nucleic acid metabolic process	13	8
Organelle organization	2	0
Organic acid metabolic process	19	33
Primary metabolic process	86	80
Protein metabolic process	33	11
Regulation of cellular process	0	1
Response to stress	5	22
Ribosome biogenesis	32	2
Secondary metabolic process	1	1
Sulfur metabolic process	2	6
Transmembrane transport	5	3
Cellular component
Cell	124	71
Cell projection	1	0
External encapsulating structure	1	4
Extracellular region	3	1
Intracellular	93	47
Intracellular part	80	33
Membrane	37	19
Organelle	38	6
Protein complex	45	35
Ribonucleoprotein complex	32	2
Molecular function
Binding	110	97
Catalytic	107	154
Enzyme regulator	1	0
Ion binding	59	66
Lipid binding	1	1
Nucleic acid binding	58	31
Protein binding	1	2
Signal transducer	5	8
Structural constituent of ribossome	31	1
Substrate-specific transporter	2	0
Translation regulator	1	0
Transmembrane transporter	68	45

ISSN: 1869-2044