Fig. 1From: Gene modification of Escherichia coli and incorporation of process control to decrease acetate accumulation and increase ʟ-tryptophan productionSimplified model for the acetate biosynthesis pathway in Escherichia coli. The key enzymes for acetate synthesis involved are shown in the figure: PPS (phosphoenolpyruvate synthase), PFK (phosphofructokinase), PCK (phosphoenolpyruvate carboxykinase), PDH (pyruvate dehydrogenase), LDH (lactate dehydrogenase), PFL (pyruvate formate-lyase), POX (pyruvate oxidase), ACS (acetyl-CoA synthetase), PTA (phosphotransacetylase), ACK (acetate kinase)Back to article page