Fig. 5

Heat maps summarizing the differential expression of the key genes responsible in glycolysis and TCA cycle during the production phase of A. terreus. The number in the box indicates the differential gene expression level compared with that at the starting time that the gene was expressed (48 or 72 h). The green box represents the upregulation of the gene. The red box represents the downregulation of the gene. The black box indicates a slight change in gene expression level (log2(fold_change) less than 2). ND represents the fragments per kilobase per million reads (FPKM) at that time was zero (no expression). a Glycolytic cluster, b citrate isomer, c itaconic acid cluster, d glyoxylate/dicarboxylate metabolism, and e ATP synthase cluster