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Table 1 Significantly differentially expressed proteins between control and cFP-treated S. aureus

From: Analysis of the influence of cyclo (L-phenylalanine-L-proline) on the proteome of Staphylococcus aureus using iTRAQ

Gene ID

Control

cFP

log2_FC (cFP/CK)

P value

FDR

Description

Q2FVJ6

0.9643

2.5560

1.4063

0.0003

0.0579

adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA

Q2FVJ7

0.8913

1.8340

1.0410

0.0005

0.0701

biotin synthase BioB

A0A0H2I6U0

1.0313

1.9283

0.9028

0.0256

0.2943

ribonuclease M5

G5JJ45

1.0313

1.9283

0.9028

0.0256

0.2943

ribonuclease M5

A0A1E5JK13

1.0313

1.9283

0.9028

0.0256

0.2943

ribonuclease M5

Q2G0T1

1.0313

1.9283

0.9028

0.0256

0.2943

ribonuclease M5

Q9RFJ6

0.9387

1.6023

0.7715

0.0001

0.0420

HTH-type transcription factor (TF) Rot

Q2G0K2

0.9647

1.3957

0.5329

0.0013

0.1087

acetyl-CoA acetyltransferase

Q2FZW2

1.2047

1.7410

0.5313

0.0458

0.3567

NifU-like protein, Nitrogen fixation protein NifU

Q2FY46

0.8717

1.2583

0.5297

0.0348

0.3185

exodeoxyribonuclease 7 large subunit

Q2FZU3

1.0110

1.3960

0.4655

0.0038

0.1835

glycerophosphodiester phosphodiesterase

Q2G1P3

1.1097

1.5273

0.4609

0.0439

0.3501

oleate hydratase

Q2G0V3

0.8693

1.1930

0.4566

0.0118

0.2372

cystathionine beta-lyase

Q2G1U0

0.9663

1.3233

0.4536

0.0090

0.2372

chain a, molecular mechanism and evolution of guanylate kinase regulation by (p)ppgpp

Q2G002

1.0747

1.4667

0.4487

0.0478

0.3627

3-dehydroquinase

Q9F0R1

1.1597

1.5650

0.4325

0.0176

0.2821

HTH-type TF SarR

Q2G024

1.1650

1.5607

0.4218

0.0418

0.3463

ribonuclease R

Q2G228

0.9853

1.3023

0.4024

0.0430

0.3495

purine nucleoside phosphorylase

A0A0Y9ARI8

1.1453

1.5100

0.3988

0.0323

0.3133

Maltose operon transcriptional repressor MalR, LacI family

Q2FY63

1.1453

1.5100

0.3988

0.0323

0.3133

LacI family TF

Q2FXI5

1.0217

1.3190

0.3685

0.0208

0.2879

peptidase M28

Q2G0R1

0.9127

1.1760

0.3657

0.0199

0.2836

hypoxanthine phosphoribosyl transferase

Q2FY16

1.1943

1.5247

0.3523

0.0440

0.3501

deoxyribonuclease IV

Q2G1D0

0.9067

1.1473

0.3396

0.0101

0.2372

acetyl-CoA acetyltransferase

Q2FWG9

1.0047

1.2707

0.3389

0.0474

0.3621

CsoR family TF

Q2FWY9

1.0640

1.3377

0.3302

0.0041

0.1835

glutamyl-tRNA(Gln) amidotransferase

Q2FYZ0

1.0453

1.3063

0.3216

0.0045

0.1835

glutathione peroxidase

Q2FX00

1.0497

1.3063

0.3156

0.0221

0.2879

glutamine amidotransferase

Q2FXG1

1.0327

1.2837

0.3139

0.0329

0.3133

GTP cyclohydrolase II

A0A1E5JEN8

1.0327

1.2837

0.3139

0.0329

0.3133

3,4-dihydroxy-2-butanone-4-phosphate synthase

Q2FWB8

1.0053

1.2487

0.3127

0.0015

0.1138

purine nucleoside phosphorylase, partial

Q2FXN6

0.9707

1.2030

0.3096

0.0056

0.1870

DNA-binding response TF

Q2FVW7

1.0340

1.2800

0.3079

0.0151

0.2698

acyl-CoA dehydrogenase, N-terminal domain protein

Q2G101

0.9607

1.1887

0.3072

0.0010

0.0897

Phosphoglycerate mutase family protein

Q2FY51

1.0273

1.2697

0.3055

0.0315

0.3133

dihydrolipoyl dehydrogenase

Q2FWG2

0.9450

1.1630

0.2995

0.0300

0.3112

hydroxyethylthiazole kinase

Q2G202

0.9307

1.1403

0.2931

0.0399

0.3423

Hemoglobin-like protein HbO

Q2G0V7

0.9817

1.1963

0.2853

0.0116

0.2372

carboxylesterase

Q2G0Z5

1.0040

1.2163

0.2768

0.0371

0.3336

NADPH-dependent oxidoreductase

A0A077UYP2

0.9973

1.2070

0.2753

0.0050

0.1856

Free methionine-(R)-sulfoxide reductase

Q2FZY5

1.1173

1.3457

0.2683

0.0305

0.3133

cysteine desulfurase

Q2G241

0.9477

1.1390

0.2653

0.0060

0.1920

glutamate--tRNA ligase

Q2FVT6

1.0117

1.2153

0.2646

0.0197

0.2834

imidazolonepropionase

Q2FW23

0.9600

0.7923

− 0.2769

0.0171

0.2811

30S ribosomal protein S5

Q2FUX7

1.0367

0.8457

− 0.2938

0.0326

0.3133

arginine deiminase ArcA

Q2G2E9

0.9540

0.7770

− 0.2961

0.0215

0.2879

TIGR04141 family sporadically distributed protein

Q2FVG3

0.9147

0.7440

− 0.2979

0.0292

0.3102

carboxylesterase

Q2FXH8

0.9857

0.7977

− 0.3053

0.0001

0.0318

Uncharacterised protein

Q2G261

1.0030

0.8057

− 0.3161

0.0256

0.2943

superoxide dismutase

Q2FZA1

0.9723

0.7793

− 0.3192

0.0195

0.2834

GNAT family N-acetyltransferase

Q2G0S5

1.0157

0.8090

− 0.3282

0.0001

0.0318

stage V sporulation protein G

Q2FXP2

1.0137

0.8057

− 0.3313

0.0088

0.2372

Glyceraldehyde 3-phosphate dehydrogenase

Q2FZP9

0.9203

0.7267

− 0.3409

0.0447

0.3529

2′-5′ RNA ligase

P0A0G2

1.0553

0.8320

− 0.3430

0.0424

0.3468

50S ribosomal protein L30, partial

Q2FVT2

1.0050

0.7917

− 0.3442

0.0016

0.1153

formimidoylglutamase

Q2FVN2

1.1210

0.8780

− 0.3525

0.0481

0.3627

Hsp20/alpha crystallin family protein

Q2FVE0

1.0553

0.8263

− 0.3529

0.0008

0.0857

Alkyl hydroperoxide reductase AhpD

A0A0H3JWD7

0.9387

0.7340

− 0.3548

0.0339

0.3179

pathogenicity island protein

Q2FWB1

0.9870

0.7653

− 0.3670

0.0001

0.0318

oxidoreductase

A0A0H3JPH0

0.9910

0.7683

− 0.3672

0.0469

0.3601

UDP-N-acetylglucosamine 4,6-dehydratase

Q2G1K7

0.8443

0.6463

− 0.3855

0.0463

0.3583

capsular polysaccharide synthesis enzyme CapB

Q2G168

0.8967

0.6863

− 0.3857

0.0195

0.2834

peptide ABC transporter permease

Q7X2S2

1.0727

0.8140

− 0.3981

0.0046

0.1835

carbamate kinase 2 ArcC2

A0A1E5JBN2

1.0297

0.7493

− 0.4585

0.0412

0.3457

SH3-like domain protein

Q2FYS7

1.0113

0.7357

− 0.4591

0.0004

0.0639

iron-sulfur cluster biosynthesis family protein

Q2FYH7

0.9120

0.6453

− 0.4990

0.0128

0.2423

chromosome replication protein DnaD

A0A0U1MPU9

0.9673

0.6643

− 0.5421

0.0164

0.2793

Putative staphylococcal protein

Q2FV95

1.1630

0.7903

− 0.5573

0.0348

0.3185

L-serine dehydratase, iron-sulfur-dependent subunit alpha

Q2G1I8

1.1310

0.7617

− 0.5704

0.0057

0.1870

Uncharacterised protein

A0A1Q8DFZ6

1.0253

0.6903

− 0.5707

0.0245

0.2943

Uncharacterised protein

Q2G2J7

1.0233

0.6773

− 0.5953

0.0123

0.2372

Uncharacterised protein

A0A133QBW6

1.0233

0.6773

− 0.5953

0.0123

0.2372

Uncharacterised protein

Q2FVV2

1.0243

0.6513

− 0.6532

0.0028

0.1539

MurR/RpiR family TF

A0A1E5JI47

1.0243

0.6513

− 0.6532

0.0028

0.1539

helix-turn-helix domain, rpiR family protein

A0A0H3JNW6

0.9730

0.6153

− 0.6611

0.0116

0.2372

Uncharacterised protein

Q2G189

1.1733

0.7290

− 0.6866

0.0276

0.3068

virulence factor EsxA

Q2FV94

1.2410

0.6990

− 0.8281

0.0120

0.2372

L-serine dehydratase, iron-sulfur-dependent subunit beta

Q2G1K9

1.1357

0.6363

− 0.8357

0.0027

0.1539

bifunctional acetaldehyde-CoA/alcohol dehydrogenase

P0C818

1.0510

0.5730

− 0.8752

0.0152

0.2698

PsmA4, Phenol-soluble modulin alpha 4 peptide

A0A0Z0SZ51

0.9583

0.4723

− 1.0207

0.0186

0.2821

Lipase

Q2FYU5

1.0350

0.4783

− 1.1135

0.0085

0.2372

30S ribosomal protein S14

Q2FZA4

1.3880

0.6073

− 1.1924

0.0106

0.2372

phenol soluble modulin Psm

Q2G2H0

1.1243

0.4717

− 1.2532

0.0106

0.2372

TF

Q2G2F5

0.9063

0.3073

− 1.5602

0.0348

0.3185

UDP-GlcNAc 2-epimerase