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Table 1 Response surface methodology experimental design showing the code and levels of the two tested variables

From: Quorum sensing involvement in response surface methodology for optimisation of sclerotiorin production by Penicillium sclerotiorum in shaken flasks and bioreactors

 

Levels

α = 0.5

Factors

Code

− 1

0

1

− α

+α

Concentration/percentage of added extract %(vol/vol)

A

0.0375

0.075

0.1125

0

0.15

Time of addition

B

1.5

3

4.5

0

6