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Table 2 The communities identified from the co-fitness protein network in this study and the corresponding GO molecular functions

From: Co-fitness analysis identifies a diversity of signal proteins involved in the utilization of specific c-type cytochromes

Community

Proteins

p value

Benjamini

GO molecular function

1

30

2.16E-08

4.96E-07

Heme binding

9.40E-05

0.001080277

Iron ion binding

0.001139293

0.008701481

Electron carrier activity

0.002121235

0.012135814

Cytochrome-c oxidase activity

0.022744537

0.100425179

NADH dehydrogenase (ubiquinone) activity

2

22

0.00970885

0.35

Flavin adenine dinucleotide binding

3

20

4.88E-04

0.018387353

Sulfate transmembrane-transporting ATPase activity

0.004176498

0.076440107

Pyridoxal phosphate binding

4

29

3.35E-10

4.03E-09

Signal transducer activity

3.40E-05

2.04E-04

Receptor activity

1.84E-04

7.37E-04

Structural molecule activity

5

16

2.21E-07

1.76E-06

Phosphorelay response regulator activity

1.99E-05

7.95E-05

Phosphorelay sensor kinase activity

0.009690909

0.025634178

DNA binding

6

16

——

——

No statistically significant result

7

10

6.91E-05

3.45E-04

NADH dehydrogenase (ubiquinone) activity

0.001796762

0.004485852

Succinate dehydrogenase activity

0.001796762

0.004485852

FMN binding

8

42

8.54E-08

2.65E-06

Electron carrier activity

6.22E-05

9.63E-04

Metal ion binding

9

11

0.001306437

0.02197882

Catalytic activity

0.001306437

0.02197882

Heme transporter activity

0.016843589

0.134449855

Protein disulfide oxidoreductase activity

10

3

0.022988506

0.022988506

Diguanylate cyclase activity

11

4

——

——

No statistically significant result